Katarzyna Anna Ludwik, Lina Hellwig, Tanja Fisch, Jorg Contzen, Claudia Schaar, Philipp Mergenthaler, Harald Stachelscheid
Bcl-2-associated X protein (BAX) and Blc-2 homologous antagonist killer 1 (BAK) are two pro-apoptotic members of BCL2 family. Here, two BAX/BAK double knock- out human induced pluripotent stem cell lines (iPSC) we generated using CRISPR-Cas9 to generate apoptosis incompetent cell lines. The resulting cell lines were karyotypically normal, had typical morphology and expressed typical markers for the undifferentiated state.
Stem Cell Research 76 (2024) 103377
