Knowledge insights

A powerful duo - gene editing meets hiPSC

Gene editing, especially using the CRISPR-Cas9 system, represents a key technological breakthrough in recent scientific history – but it isn’t the only important advance. Human-induced pluripotent stem cells (hiPSCs) are another powerful tool that has greatly propelled new research and therapeutic strategies in fields including...
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The versatility of Cas proteins for DNA editing and beyond

The CRISPR-Cas system is a key gene editing tool that has revolutionised how we manipulate DNA, providing the simplest, most efficient, and adaptable approach yet to making gene edits. These systems – originating in bacteria as a form of adaptive immunity – can be categorised into six types...
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