Deep expertise. Proven services.

We support scientists on their journey to scientific breakthroughs with our cutting-edge technologies and optimised, flexible services. By combining our proprietary GRID technology — which is at the core of our automated single-cell isolation and handling solutions — with our expert team of cell scientists, we can help you to elevate your genome engineering projects to new heights of success.

Our Services

Accelerate your iPSC and genome-engineering projects with our comprehensive range of services, expertly delivered by an experienced team. We ensure flexibility, precision, and accuracy in every step of your project journey.

Expertly executed knock-outs and knock-ins

Precise gene-tagging
Accurate SNP/ mutation insertion and correction

Our offering extends from initial project consultancy through to obtaining appropriately edited clonal lines. With us beside you, experience the removal of uncertainties and a smooth, efficient workflow in your genome-editing projects.

We guarantee the generation of truly clonal iPSC lines through our proprietary GRID technology. With whole-chamber imaging, you can document the process from a single cell to monoclonal colony in a fully transparent and automated process. Our fully streamlined pipeline provides you with clonal lines, achieving industry-leading cloning efficiencies across a broad range of genetically diverse iPSC lines.

Our GRID technology forms the core of our single-cell isolation and handling solutions that we use to complete iPSC and genome-engineering projects for our customers. GRID brings many benefits to our products and services, including:

Automated single-cell isolation: GRID simplifies the process of separating and capturing individual cells.
High reliability: It offers immediate and accurate in-chamber verification of monoclonality.
Exceptional optical clarity: The GRID technology is designed for clear, unobstructed viewing of cells.
No edge effects: Provides exceptional optical clarity: The GRID technology is designed for clear, unobstructed viewing of cells.

Click here, for more information about GRID, and our range of solutions that enable cell isolation feeding and harvesting, monoclonality verification, clone tracking, and cell imaging.

Paper

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Pellentesque nec mi risus. In porttitor iaculis mauris quis posuere.

Case Study

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Pellentesque nec mi risus. In porttitor iaculis mauris quis posuere.

Testimonial

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Pellentesque nec mi risus. In porttitor iaculis mauris quis posuere.

Our customers

We take pride in supporting a diverse community of scientists and researchers. Our customers range from ambitious startups to established academic institutes and globally recognised pharmaceutical companies who trust our team and technology to support their workflows, from streamlining CRISPR-based genome-engineering projects, to single-cell omics. Whether they’re focusing on fundamental cellular research or pursuing cutting-edge therapeutic discoveries, our custom services and easy-to-use platforms have proven to be a valuable asset in accelerating their work.

“Using the isoCell for our single cell cloning work has been easy and reliable from the get-go and has seamlessly been incorporated into our pipeline. The procedures are gentle for the cells and we see extremely good survival rates allowing a large number of clones to be screened. The customer service we have received is second to none.”

Louisa Emms, Research ScientistThe Native Antigen Company (Part of LGC Clinical Diagnostics)

“After a few rounds of optimization, the Single-Cell Cloning Platform provided by IotaSciences has proven to be a game-changer for our company. It allowed us to dramatically increase the throughput of genetically modified hESCs clone screening, accelerating our experimental workflow".

Davide Monducci, Research ScientistIRBM

“We have produced mutant iPSC lines with more traditional flow-sorting approaches, but this is very tedious with often limited returns with regards to cell quality and clonality. iotaSciences' knowledge-driven approach and their streamlined workflow, has allowed us to quickly obtain desired clones and move our project forward. Especially the visual confirmation of obtaining true single-cell clones is a massive benefit."

Dr. Jussi-Pekka Tolonen, Clinical ResearcherUniversity of Oulu

“It was impressive that cells grew from a single cell within the GRIDs, which was like magic as we could not grow the cell in 96 well plates."

Dr. Yoshi Itoh, Associate Professor and Principal InvestigatorUniversity of Oxford

“The Cloning platform from iotaSciences has transformed our workflow to derive gene-edited hiPSC clones. The system is surprisingly small with an impressive level of automation and an intuitive user-interface. We have consistently obtained good outcomes and since everything is miniaturised, down to nanolitre volumes, consumables costs are minimal.”

University of Bonn