Further results from collaboration with SEISMIC facility at the University of Surrey demonstrate a novel, accessible, and high-throughput way to obtain single-cell lipid profiles
Oxford (UK), October 31, 2024: iotaSciences, the Oxford-based leader in single-cell biology handling solutions announced today the publication of validation work related to the use of its isoPick™ Single-Cell Picking Platform for an automated and accessible microfluidic workflow for single-cell lipidomics.
The publication in Analytical Chemistry by researchers at the University of Surrey SEISMIC facility (UK), accessible online (DOI: https://pubs.acs.org/doi/10.1021/acs.analchem.4c03435#), marks the first report of a novel, accessible, and high-throughput way to obtain single-cell lipid profiles. Lipids play crucial roles in various biological processes, including cell membrane structure, signaling pathways, energy storage, and metabolism. As such, lipidomics has emerged as a vital field in modern biology and medicine with a particular focus on single-cell analysis capabilities to fully understand heterogeneity present within a cell population. Understanding differences and changes in cell lipid profiles is important in particular for the treatment of infectious diseases, allergy and cancer.
Professor Melanie Bailey from the department of Chemistry at the University of Surrey said: “We have been very pleased with the continued progress from our collaborative efforts with iotaSciences since we reported on first encouraging results related to the isoPick™ instrument over a year ago. We now have in hand an automated and easily accessible workflow for investigating cellular lipid metabolism at the single-cell level, thereby advancing our understanding of lipid-related diseases and facilitating the development of targeted therapeutic interventions.”
“We are thrilled to have been able to contribute to this important methodology development publication in Analytical Chemistry”, Dr Michael Lutz, CEO at iotaSciences, commented. “We are eagerly excited to further help the field of single-cell lipidomics to evolve by providing the first of its kind Single-Cell Picking Platform, allowing automation and high-throughput handling with an easy-to-use end-to-end cell isolation solution.”
About iotaSciences (https://iotasciences.com):
iotaSciences is a spin-out from the University of Oxford (UK), founded in 2016 by scientists from the Department of Engineering Science and the Sir William Dunn School of Pathology. Since its inception, iotaSciences has been committed to offer researchers highly user-friendly, reliable, and powerful single cell handling technologies and solutions with unique capabilities that greatly simplify and facilitate breakthrough advances in cell biology and gene therapy.
For further information please contact:
iotaSciences Ltd.
Dr Michael Lutz, Chief Executive Officer
Tel: +44 (1865) 309630
Email: info@iotasciences.com